Supporters say sanctions deny Iran revenue that could fund its nuclear program and regional proxies; critics say they have not halted enrichment and have hardened Tehran's posture.
A strategy of squeezing Iran's economy with sanctions to force its leaders back to the bargaining table on tougher terms.
The campaign frames the current debate over whether to keep pressure in place, ease it as part of new talks, or pair it with direct diplomacy.
The U.S. penalizes foreign companies and banks that do business with sanctioned Iranian entities, effectively cutting Iran off from much of the global financial system.
Targeted measures bar Iran from selling oil, petrochemicals, and metals on world markets and block its access to dollar-denominated transactions.
A look at the history, stakes, and competing arguments behind U.S.-Iran nuclear diplomacy.
Read the guide →Policymakers are divided over whether face-to-face talks with Tehran offer the best path to curbing its advancing nuclear capabilities.
Read the brief →